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1) To demonstrate the potential value of pulse oximetry, systolic rise time and
Dermastat in people with diabetes.
2) To assess if pulse oximetry, systolic rise time and Dermastat are the definitive
investigation for applications mentioned above.
3) To establish whether pulse oximetry as bedside screening tool for peripheral
arterial disease in people with/out diabetes and diabetic foot infection by
determining the diagnostic accuracy, utility, reproducibility and intraobserver variability.
4) To establish whether systolic rise time measured on ultrasound is a novel
screening tool for peripheral arterial disease in people with/out diabetes and
diabetic foot infection by determining the diagnostic accuracy, utility,
reproducibility and intra-observer variability.
Thesis Summary – Keeley Foley
Page 3 of 5
5) To establish the clinical utility of dermastat to assess peripheral autonomic
neuropathy.
6) To establish if Genome Sequencing of bacteria from infected foot ulcers
provides a more rapid and less expensive method for clinical identification of
bacteria of foot ulcers for targeted antibiotic therapy
To use Data Bases: PubMed, Embasluve, OVID, Cochrane, NIHR library
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